Review





Similar Products

nf κb inhibitor hy 13453  (MedChemExpress)
98
MedChemExpress nf κb inhibitor hy 13453
Nf κb Inhibitor Hy 13453, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nf κb inhibitor hy 13453/product/MedChemExpress
Average 98 stars, based on 1 article reviews
nf κb inhibitor hy 13453 - by Bioz Stars, 2026-02
98/100 stars
  Buy from Supplier
nf κb inhibitor  (MedChemExpress)
98
MedChemExpress nf κb inhibitor
Nf κb Inhibitor, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nf κb inhibitor/product/MedChemExpress
Average 98 stars, based on 1 article reviews
nf κb inhibitor - by Bioz Stars, 2026-02
98/100 stars
  Buy from Supplier
nf κb inhibitor bay  (MedChemExpress)
98
MedChemExpress nf κb inhibitor bay
Nf κb Inhibitor Bay, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nf κb inhibitor bay/product/MedChemExpress
Average 98 stars, based on 1 article reviews
nf κb inhibitor bay - by Bioz Stars, 2026-02
98/100 stars
  Buy from Supplier
nf κb inhibitor  (TargetMol)
94
TargetMol nf κb inhibitor
Nf κb Inhibitor, supplied by TargetMol, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nf κb inhibitor/product/TargetMol
Average 94 stars, based on 1 article reviews
nf κb inhibitor - by Bioz Stars, 2026-02
94/100 stars
  Buy from Supplier
nf κb inhibitor bay 11 7082  (MedChemExpress)
98
MedChemExpress nf κb inhibitor bay 11 7082
Functions of PEAK1 on the <t>HIF-1α/STAT3/NF-κB</t> pathway activation in PCa cells. A WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression. B , C WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 knocking down. D WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 cells with PEAK1 overexpression and co-culturing with THP1 cells. E , F WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression and LW6, Stattic or <t>Bay</t> <t>11–7082</t> treatment. N = 3. * stands for p < 0.05, ** stands for p < 0.01, *** stands for p < 0.001
Nf κb Inhibitor Bay 11 7082, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nf κb inhibitor bay 11 7082/product/MedChemExpress
Average 98 stars, based on 1 article reviews
nf κb inhibitor bay 11 7082 - by Bioz Stars, 2026-02
98/100 stars
  Buy from Supplier
nf κb inhibitor bay11 7082  (MedChemExpress)
98
MedChemExpress nf κb inhibitor bay11 7082
Functions of PEAK1 on the <t>HIF-1α/STAT3/NF-κB</t> pathway activation in PCa cells. A WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression. B , C WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 knocking down. D WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 cells with PEAK1 overexpression and co-culturing with THP1 cells. E , F WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression and LW6, Stattic or <t>Bay</t> <t>11–7082</t> treatment. N = 3. * stands for p < 0.05, ** stands for p < 0.01, *** stands for p < 0.001
Nf κb Inhibitor Bay11 7082, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nf κb inhibitor bay11 7082/product/MedChemExpress
Average 98 stars, based on 1 article reviews
nf κb inhibitor bay11 7082 - by Bioz Stars, 2026-02
98/100 stars
  Buy from Supplier
nf κb inhibitor bay 11 7821  (MedChemExpress)
98
MedChemExpress nf κb inhibitor bay 11 7821
Functions of PEAK1 on the <t>HIF-1α/STAT3/NF-κB</t> pathway activation in PCa cells. A WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression. B , C WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 knocking down. D WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 cells with PEAK1 overexpression and co-culturing with THP1 cells. E , F WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression and LW6, Stattic or <t>Bay</t> <t>11–7082</t> treatment. N = 3. * stands for p < 0.05, ** stands for p < 0.01, *** stands for p < 0.001
Nf κb Inhibitor Bay 11 7821, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nf κb inhibitor bay 11 7821/product/MedChemExpress
Average 98 stars, based on 1 article reviews
nf κb inhibitor bay 11 7821 - by Bioz Stars, 2026-02
98/100 stars
  Buy from Supplier
nf κb pathway inhibitor bay 11 7082  (MedChemExpress)
98
MedChemExpress nf κb pathway inhibitor bay 11 7082
Functions of PEAK1 on the <t>HIF-1α/STAT3/NF-κB</t> pathway activation in PCa cells. A WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression. B , C WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 knocking down. D WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 cells with PEAK1 overexpression and co-culturing with THP1 cells. E , F WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression and LW6, Stattic or <t>Bay</t> <t>11–7082</t> treatment. N = 3. * stands for p < 0.05, ** stands for p < 0.01, *** stands for p < 0.001
Nf κb Pathway Inhibitor Bay 11 7082, supplied by MedChemExpress, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/nf κb pathway inhibitor bay 11 7082/product/MedChemExpress
Average 98 stars, based on 1 article reviews
nf κb pathway inhibitor bay 11 7082 - by Bioz Stars, 2026-02
98/100 stars
  Buy from Supplier

Image Search Results


Functions of PEAK1 on the HIF-1α/STAT3/NF-κB pathway activation in PCa cells. A WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression. B , C WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 knocking down. D WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 cells with PEAK1 overexpression and co-culturing with THP1 cells. E , F WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression and LW6, Stattic or Bay 11–7082 treatment. N = 3. * stands for p < 0.05, ** stands for p < 0.01, *** stands for p < 0.001

Journal: European Journal of Medical Research

Article Title: PEAK1 promotes prostate cancer progression and docetaxel resistance by mediating the polarization of tumor-associated macrophages

doi: 10.1186/s40001-025-03568-2

Figure Lengend Snippet: Functions of PEAK1 on the HIF-1α/STAT3/NF-κB pathway activation in PCa cells. A WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression. B , C WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 knocking down. D WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 cells with PEAK1 overexpression and co-culturing with THP1 cells. E , F WB was conducted to test the protein levels of HIF-1α, PD-L1, p -STAT3, and p –p65 in PC3 and DU145 cells with PEAK1 overexpression and LW6, Stattic or Bay 11–7082 treatment. N = 3. * stands for p < 0.05, ** stands for p < 0.01, *** stands for p < 0.001

Article Snippet: The PC3 and DU145 cells were treated with the HIF-1α inhibitor LW6 (10 μM, #HY-13671, MedChemExpress) [ ]; the STAT3 inhibitor Stattic (10 μM, #HY-13818, MedChemExpress) [ ]; the NF-κB inhibitor Bay 11–7082 (15 μM, #HY-13453, MedChemExpress) [ ]; and increasing doses of enzalutamide (5 μM, 10 μM, 20 μM, and 40 μM, #HY-70002, MedChemExpress) [ ] for 24 h.

Techniques: Activation Assay, Over Expression

Mechanistic diagram of PEAK1 in PCa. Summary diagram of the functions and mechanisms of PEAK1 in PCa. Upregulated PEAK1 promotes the HIF-1α/STAT3/NF-κB pathway activation, thus enhancing tumor proliferation, migration, EMT, and reducing apoptosis, docetaxel/enzalutamide sensitivity. PEAK1 enhances CCL2, IL-6 and PD-L1 expression from PCa cells, which mediate “M2” polarization of TAMs and inducing TGF- β expression from TAMs. TGF- β can act on PCa cells and induce PEAK1 upregulation

Journal: European Journal of Medical Research

Article Title: PEAK1 promotes prostate cancer progression and docetaxel resistance by mediating the polarization of tumor-associated macrophages

doi: 10.1186/s40001-025-03568-2

Figure Lengend Snippet: Mechanistic diagram of PEAK1 in PCa. Summary diagram of the functions and mechanisms of PEAK1 in PCa. Upregulated PEAK1 promotes the HIF-1α/STAT3/NF-κB pathway activation, thus enhancing tumor proliferation, migration, EMT, and reducing apoptosis, docetaxel/enzalutamide sensitivity. PEAK1 enhances CCL2, IL-6 and PD-L1 expression from PCa cells, which mediate “M2” polarization of TAMs and inducing TGF- β expression from TAMs. TGF- β can act on PCa cells and induce PEAK1 upregulation

Article Snippet: The PC3 and DU145 cells were treated with the HIF-1α inhibitor LW6 (10 μM, #HY-13671, MedChemExpress) [ ]; the STAT3 inhibitor Stattic (10 μM, #HY-13818, MedChemExpress) [ ]; the NF-κB inhibitor Bay 11–7082 (15 μM, #HY-13453, MedChemExpress) [ ]; and increasing doses of enzalutamide (5 μM, 10 μM, 20 μM, and 40 μM, #HY-70002, MedChemExpress) [ ] for 24 h.

Techniques: Activation Assay, Migration, Expressing